diff --git a/dlls/rpcrt4/Makefile.in b/dlls/rpcrt4/Makefile.in
index 2aa2a5376aa..822e6ded35d 100644
--- a/dlls/rpcrt4/Makefile.in
+++ b/dlls/rpcrt4/Makefile.in
@@ -1,4 +1,4 @@
-EXTRADEFS = -D_RPCRT4_ -DMSWMSG
+EXTRADEFS = -DMSWMSG
 MODULE    = rpcrt4.dll
 IMPORTLIB = rpcrt4
 IMPORTS   = uuid advapi32